by Bed bugs are causing major problems in multiple cities across Kentucky, USA. In 2025, pest control companies have reported serious infestations in at least five key cities and metro areas throughout the state. These tiny pests are spreading rapidly, especially in areas with high travel activity, older infrastructure, and dense populations.
Lexington: The Epicenter of the Problem
Lexington continues to top the list as the most bed bug-infested city in Kentucky. It also regularly appears on national rankings of cities with the worst bed bug issues across the United States.
Lexington’s mix of urban living, frequent travel, and numerous apartment complexes makes it especially vulnerable to infestations. The pests can easily move between units and spread undetected.
Louisville: Kentucky’s Largest City Under Siege
Louisville, the most populous city in the state, has become a major hotspot for bed bugs. Pest control companies report a high volume of treatment calls here.
Factors such as its large population, active tourism industry, and widespread shared housing make Louisville a prime location for infestations.
Paducah: A Smaller City Facing a Big Problem
Located in western Kentucky, Paducah has also seen a significant rise in bed bug cases. Despite being smaller than Lexington and Louisville, it has gained attention in both state and national reports.
Older housing stock and limited public awareness are believed to contribute to the city’s bed bug problem.
Cape Girardeau–Paducah–Harrisburg Metro Area: A Regional Concern
The broader metro region that includes Paducah and extends into parts of Missouri and Illinois is also experiencing widespread infestations. This shows that bed bugs are not just a city issue but a regional concern.
The mobility of people across city and state lines plays a major role in spreading the pests beyond urban centers.
Other High-Traffic Cities at Risk
Beyond the top cities, several high-traffic towns and tourist destinations in Kentucky are reporting growing bed bug concerns. Locations near airports, bus terminals, hotels, and motels are particularly susceptible, especially during peak travel seasons.
Why Are Bed Bugs Spreading So Quickly in Kentucky?
Several factors contribute to the rise of bed bug infestations across the state:
- Increased Travel: Bed bugs often hitch rides in luggage, clothing, and personal items.
- Urban Housing: Shared walls and multi-unit living spaces help them move easily between rooms.
- Hot, Humid Weather: Kentucky’s summer climate accelerates breeding cycles.
- Aging Buildings: Older homes and hotels provide more hiding places for bed bugs.
How Are Cities Responding?
Kentucky cities are actively working to contain and reduce infestations through a combination of strategies:
- Public Alerts: Health departments are issuing warnings and prevention tips.
- Professional Treatments: Pest control companies are ramping up inspections and services.
- Education Campaigns: Residents are being trained to recognize early signs of infestation and prevent spread.
In 2025, bed bugs have become a growing threat in urban and metro regions across Kentucky. Lexington, Louisville, and Paducah are among the most impacted, but no area is immune. With increased awareness and coordinated responses, state and local authorities aim to bring the situation under control.
Travelers are urged to remain cautious, inspect accommodations, and take preventive steps to avoid carrying the pests home.
